Kirk R Henne Selected Research

Iduronic Acid (Iduronate)

1/2022	Molecular architecture determines brain delivery of a transferrin receptor-targeted lysosomal enzyme.
7/2020	High-Throughput Liquid Chromatography-Tandem Mass Spectrometry Quantification of Glycosaminoglycans as Biomarkers of Mucopolysaccharidosis II.
1/2020	Brain delivery and activity of a lysosomal enzyme using a blood-brain barrier transport vehicle in mice.

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Kirk R Henne Research Topics

Disease

4	Mucopolysaccharidosis II (Hunter Syndrome) 01/2022 - 01/2020
1	Neurologic Manifestations (Neurological Manifestations) 10/2021
1	Frontotemporal Dementia (Semantic Dementia) 01/2021
1	Mucopolysaccharidoses 07/2020
1	Central Nervous System Diseases (CNS Diseases) 01/2020
1	Lysosomal Storage Diseases (Lysosomal Storage Disease) 01/2020
1	Neuroinflammatory Diseases 01/2020
1	Cardiovascular Diseases (Cardiovascular Disease) 04/2015
1	Autoimmune Diseases (Autoimmune Disease) 01/2015
1	Inflammation (Inflammations) 01/2015
1	Rodent Diseases 01/2015
1	Asthma (Bronchial Asthma) 05/2010
1	Allergic Rhinitis 05/2010
1	Drug-Related Side Effects and Adverse Reactions 06/2005
1	Liver Failure 02/2005

Drug/Important Bio-Agent (IBA)

4	EnzymesIBA 01/2022 - 01/2020
3	Iduronic Acid (Iduronate)IBA 01/2022 - 01/2020
2	GlycosaminoglycansIBA 10/2021 - 07/2020
1	Proteins (Proteins, Gene)FDA Link 01/2021
1	ProgranulinsIBA 01/2021
1	Biomarkers (Surrogate Marker)IBA 07/2020
1	Heparitin Sulfate (Heparan Sulfate)IBA 07/2020
1	Dermatan SulfateIBA 07/2020
1	DisaccharidesIBA 07/2020
1	LipidsIBA 01/2020
1	Proprotein Convertase 9IBA 04/2015
1	N- (1- (7- fluoro- 2- (pyridin- 2- yl)quinolin- 3- yl)ethyl)- 9H- purin- 6- amineIBA 01/2015
1	Protein Kinases (Protein Kinase)IBA 01/2015
1	Cytochrome P-450 CYP3AIBA 05/2010
1	Pharmaceutical PreparationsIBA 06/2005
1	nefazodone (Serzone)FDA LinkGeneric 02/2005
1	Antidepressive Agents (Antidepressants)IBA 02/2005

Therapy/Procedure

1	Enzyme Replacement Therapy 10/2021
1	Enzyme Therapy 01/2020
1	Therapeutics 01/2020